Why Bacteriophage Encode Exotoxins and other Virulence Factors
نویسندگان
چکیده
منابع مشابه
Why Bacteriophage Encode Exotoxins and other Virulence Factors
This study considers gene location within bacteria as a function of genetic element mobility. Our emphasis is on prophage encoding of bacterial virulence factors (VFs). At least four mechanisms potentially contribute to phage encoding of bacterial VFs: (i) Enhanced gene mobility could result in greater VF gene representation within bacterial populations. We question, though, why certain genes b...
متن کاملBacteriophage control of bacterial virulence.
In 1930, Felix d’Herelle wrote “. . .the actions and reactions are not solely between these two beings, man and bacterium, for the bacteriophage also intervenes; a third living being and, hence, a third variable is introduced” (19). The contribution of bacteriophages to the pathogenicity of their bacterial hosts began to be uncovered as early as 1927, when Frobisher and Brown discovered that no...
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Bacteriophages can influence the abundance, diversity, and evolution of bacterial communities. Several bacteriophages have been reported to add virulence factors to their host and to increase bacterial virulence. However, lytic bacteriophages can also exert a selective pressure allowing the proliferation of strains with reduced virulence. This reduction can be explained because bacteriophages u...
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Numerous investigations have attempted to define those factors responsible for the virulence of Staphylococcus aureus.'" Almost all of the enzymes and exotoxins produced by staphylococci have at some time been purported to be responsible for their pathogenicity but none has been clearly demonstrated of paramount importance.'" The relation of coagulase and alpha hemolysin to the pathogenesis of ...
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ژورنال
عنوان ژورنال: Evolutionary Bioinformatics
سال: 2005
ISSN: 1176-9343,1176-9343
DOI: 10.1177/117693430500100001